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Rigosertib (ON-01910), 1g
25.901,54 RON
SKU
SKM_S1362_1g
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1with IC50of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Aktpathway and activates oxidative stress signals. Rigosertib induces apoptosisin various cancer cells. Phase 3.
| Price | 21.766,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1with IC50of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Aktpathway and activates oxidative stress signals. Rigosertib induces apoptosisin various cancer cells. Phase 3. |
