Resatorvid (TAK-242), 100mg

Resatorvid (TAK-242), 100mg

Osilodrostat (LCI699), 2mg

Osilodrostat (LCI699), 2mg

Resatorvid (TAK-242), 10mM/1mL

1.501,78 RON
SKU
SKM_S7455_10mM/1mL

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.

Mai multe informatii
Price 1.262,00 RON (preturile sunt fara TVA)
Description

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.