Limba
Romanian
Romanian
English|
Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK)with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.
| Price | 2.197,00 RON (preturile sunt fara TVA) |
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| Description |
Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK)with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases. |
