Remibrutinib, 1g

Remibrutinib, 1g

UNC2025, 5mg

UNC2025, 5mg

Remibrutinib, 10mM/1mL

3.244,01 RON
SKU
SKM_S9660_10mM/1mL

Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK)with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.

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Price 2.681,00 RON (preturile sunt fara TVA)
Description

Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK)with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.