Sapanisertib (MLN0128), 10mM/1mL

Sapanisertib (MLN0128), 10mM/1mL

(R)-(-)-Gossypol (AT-101) acetic acid, 1g

(R)-(-)-Gossypol (AT-101) acetic acid, 1g

(R)-(-)-Gossypol (AT-101) acetic acid, 50mg

3.255,84 RON
SKU
SKM_S2812_50mg

(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xLand Mcl-1with Kiof 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosisand a cytoprotective type of autophagy. Phase 2.

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Price 2.736,00 RON (preturile sunt fara TVA)
Description

(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xLand Mcl-1with Kiof 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosisand a cytoprotective type of autophagy. Phase 2.