Limba
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Quizartinib (AC220) is a second-generation FLT3inhibitor for Flt3(ITD/WT)with IC50of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosisof tumor cells. Phase 3.
Price | 1.262,00 RON (preturile sunt fara TVA) |
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Description |
Quizartinib (AC220) is a second-generation FLT3inhibitor for Flt3(ITD/WT)with IC50of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosisof tumor cells. Phase 3. |