Quisinostat (JNJ-26481585) 2HCl, 5mg

Quisinostat (JNJ-26481585) 2HCl, 5mg

Quisinostat (JNJ-26481585) 2HCl, 1g

Quisinostat (JNJ-26481585) 2HCl, 1g

Quisinostat (JNJ-26481585) 2HCl, 50mg

6.475,98 RON
SKU
SKM_S1096_50mg

Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDACinhibitor with highest potency for HDAC1 with IC50of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.

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Description

Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDACinhibitor with highest potency for HDAC1 with IC50of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.