Prim-o-glucosylcimifugin, 1mg

Prim-O-glucosylcimifugin (Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside) is a major constituent in Radix Saposhnikovia that has been long used for the treatment of pyrexia, rheumatism, and cancer in traditional Chinese medicine. It shows potential anticancer activity. Prim-O-glucosylcimifugin downregulates the mRNA and protein expression inducible NO synthase (iNOS)and cyclooxygenase 2 (COX-2)in LPS-activated RAW 264.7 macrophages in a concentration-dependent manner.