Pinometostat (EPZ5676), 1g

Pinometostat (EPZ5676), 1g

LY2090314, 5mg

LY2090314, 5mg

Pinometostat (EPZ5676), 10mM/1mL

2.470,44 RON
SKU
SKM_S7062_10mM/1mL

Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1Lwith Kiof 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.

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Description

Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1Lwith Kiof 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.