PIM447 (LGH447), 2mg

PIM447 (LGH447), 2mg

PIM447 (LGH447), 10mM/1mL

PIM447 (LGH447), 10mM/1mL

PIM447 (LGH447), 5mg

2.614,43 RON
SKU
SKM_S7985_5mg

PIM447 (LGH447) is a novel pan-PIM kinaseinhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3β, PKN1, and PKCτ, but at a significantly lower potency with IC50 between 1 and 5 μM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.

Mai multe informatii
Price 2.197,00 RON (preturile sunt fara TVA)
Description

PIM447 (LGH447) is a novel pan-PIM kinaseinhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3β, PKN1, and PKCτ, but at a significantly lower potency with IC50 between 1 and 5 μM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.