PF-543 hydrochloride, 25mg

PF-543 hydrochloride, 25mg

Prexasertib HCl (LY2606368), 2mg

Prexasertib HCl (LY2606368), 2mg

PF-543 hydrochloride, 10mM/1mL

1.501,78 RON
SKU
SKM_S7177_10mM/1mL

PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50and Kiof 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.

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Price 1.262,00 RON (preturile sunt fara TVA)
Description

PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50and Kiof 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.