Limba
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PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTORdual inhibitor with Kiof 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.
Price | 992,00 RON (preturile sunt fara TVA) |
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Description |
PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTORdual inhibitor with Kiof 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2. |