PHA-767491 HCl, 10mM/1mL

PHA-767491 HCl, 10mM/1mL

PF-04691502, 50mg

PF-04691502, 50mg

PF-04691502, 5mg

1.180,48 RON
SKU
SKM_S2743_5mg

PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTORdual inhibitor with Kiof 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.

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Description

PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTORdual inhibitor with Kiof 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.