PD173074, 1g

PD173074, 1g

SQ109, 5mg

SQ109, 5mg

PD173074, 10mM/1mL

1.501,78 RON
SKU
SKM_S1264_10mM/1mL

PD173074 is a potent FGFR1inhibitor with IC50of ~25 nM and also inhibits VEGFR2with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosisin gastric cancer cells.

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Description

PD173074 is a potent FGFR1inhibitor with IC50of ~25 nM and also inhibits VEGFR2with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosisin gastric cancer cells.