Limba
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Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1)inhibitor with IC50of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosisin cancer cell lines and inhibits tumor growth. Phase 1.
Price | 1.812,00 RON (preturile sunt fara TVA) |
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Description |
Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1)inhibitor with IC50of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosisin cancer cell lines and inhibits tumor growth. Phase 1. |