Tucatinib , 10mM/1mL

Tucatinib , 10mM/1mL

NMS-P118, 25mg

NMS-P118, 25mg

NMS-P118, 5mg

1.180,48 RON
SKU
SKM_S8363_5mg

NMS-P118 is a potent, orally available, and highly selective PARP-1inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).

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Description

NMS-P118 is a potent, orally available, and highly selective PARP-1inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).