USP25/28 inhibitor AZ1, 10mM/1mL

USP25/28 inhibitor AZ1, 10mM/1mL

MYCi361, 25mg

MYCi361, 25mg

MYCi361, 5mg

2.614,43 RON
SKU
SKM_S8905_5mg

MYCi361 is a MYCinhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 μM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy.

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Description

MYCi361 is a MYCinhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 μM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy.