Limba
|
MT-802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK)knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL).
Price | 3.434,00 RON (preturile sunt fara TVA) |
---|---|
Description |
MT-802 is a potent PROTAC that induces Bruton's tyrosine kinase (BTK)knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL). |