Limba
|
MK-5108 is a highly selective Aurora Ainhibitor with IC50of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.
Price | 27.172,00 RON (preturile sunt fara TVA) |
---|---|
Description |
MK-5108 is a highly selective Aurora Ainhibitor with IC50of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1. |