Milciclib, 1g

Milciclib, 1g

HER2-Inhibitor-1, 5mg

HER2-Inhibitor-1, 5mg

Milciclib, 10mM/1mL

3.452,19 RON
SKU
SKM_S2751_10mM/1mL

Milciclib is a potent, ATP-competitive CDKinhibitor for CDK2 with IC50of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7, it's also an inhibitor of TRKA with IC50 of 53nM. Milciclib (PHA-848125) induces cell death through autophagy. Phase 2.

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Description

Milciclib is a potent, ATP-competitive CDKinhibitor for CDK2 with IC50of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7, it's also an inhibitor of TRKA with IC50 of 53nM. Milciclib (PHA-848125) induces cell death through autophagy. Phase 2.