Limba
Romanian
Romanian
English|
MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR)inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
| Price | 827,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR)inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model. |
