LY2109761, 1g

LY2109761, 1g

DBZ (Dibenzazepine), 2mg

DBZ (Dibenzazepine), 2mg

LY2109761, 10mM/1mL

2.790,55 RON
SKU
SKM_S2704_10mM/1mL

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II)dual inhibitor with Kiof 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagyand induces apoptosis.

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Description

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II)dual inhibitor with Kiof 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagyand induces apoptosis.