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Crizotinib, 200mg

Crizotinib, 200mg

Luminespib (NVP-AUY922), 25mg

Luminespib (NVP-AUY922), 25mg

Luminespib (NVP-AUY922), 5mg

1.266,16 RON
SKU
SKM_S1069_5mg
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Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/βwith IC50of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβprotein and results in growth inhibition, autophagyand apoptosis. Phase 2.

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Price 1.064,00 RON (preturile sunt fara TVA)
Description

Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/βwith IC50of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβprotein and results in growth inhibition, autophagyand apoptosis. Phase 2.
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