Limba
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Linagliptin (GSK2118436) is a highly potent, selective DPP-4inhibitor with IC50of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagyin a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
Price | 1.707,00 RON (preturile sunt fara TVA) |
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Description |
Linagliptin (GSK2118436) is a highly potent, selective DPP-4inhibitor with IC50of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagyin a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells. |