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Lesinurad, 20mg

860,37 RON
SKU
SKM_S4640_20mg

Lesinurad (RDEA-594) is a selective uric acid reabsorptioninhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.

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Description

Lesinurad (RDEA-594) is a selective uric acid reabsorptioninhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.