Laduviglusib (CHIR-99021; CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/βinhibitor with IC50of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-cateninsignaling pathway. CHIR-99021 significantly rescues light-induced autophagyand augments GR, RORα and autophagy-related proteins.
Price | 5.442,00 RON (preturile sunt fara TVA) |
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Description |
Laduviglusib (CHIR-99021; CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3α/βinhibitor with IC50of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-cateninsignaling pathway. CHIR-99021 significantly rescues light-induced autophagyand augments GR, RORα and autophagy-related proteins. |