Limba
Romanian
Romanian
English|
KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4in development for the treatment of TLR/IL-1R–driven autoimmune diseases. KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS)-induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs).
| Price | 1.262,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4in development for the treatment of TLR/IL-1R–driven autoimmune diseases. KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS)-induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs). |
