PF-06273340, 10mg

PF-06273340, 10mg

KG-501, 10mM/1mL

KG-501, 10mM/1mL

KG-501, 10mg

1.180,48 RON
SKU
SKM_S8409_10mg

KG-501 is a cAMP response element-binding protein (CREB)inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM). It also disrupts phospho (Ser-133) CREB binding to KIX with a Ki of ≈90 μM, using concentrations of CREB that were within the linear range of the binding assay.

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Description

KG-501 is a cAMP response element-binding protein (CREB)inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM). It also disrupts phospho (Ser-133) CREB binding to KIX with a Ki of ≈90 μM, using concentrations of CREB that were within the linear range of the binding assay.