JTE-607 Dihydrochloride, 5mg

JTE-607 Dihydrochloride, 5mg

JTE-607 Dihydrochloride, 100mg

JTE-607 Dihydrochloride, 100mg

JTE-607 Dihydrochloride, 25mg

2.915,50 RON
SKU
SKM_E0314_25mg

JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis. JTE-607 is a multiple cytokine productioninhibitor that targets CPSF3and inhibits pre-mRNA processing. JTE-607 inhibits tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50 values of 11 nM, 5.9 nM, 8.8 nM, 7.3 nM and 9.1 nM, respectively.

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Price 2.450,00 RON (preturile sunt fara TVA)
Description

JTE-607 Dihydrochloride is a prodrug compound that is converted to an active form by ester hydrolysis. JTE-607 is a multiple cytokine productioninhibitor that targets CPSF3and inhibits pre-mRNA processing. JTE-607 inhibits tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50 values of 11 nM, 5.9 nM, 8.8 nM, 7.3 nM and 9.1 nM, respectively.