(+)-JQ1, 1g

(+)-JQ1, 1g

(+)-JQ1, 10mM/1mL

(+)-JQ1, 10mM/1mL

(+)-JQ1, 100mg

6.475,98 RON
SKU
SKM_S7110_100mg

(+)-JQ1 is a BET bromodomaininhibitor, with IC50of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3)target genes.

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Description

(+)-JQ1 is a BET bromodomaininhibitor, with IC50of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3)target genes.