Ceritinib, 200mg

Ceritinib, 200mg

IWP-2, 1g

IWP-2, 1g

IWP-2, 10mg

1.180,48 RON
SKU
SKM_S7085_10mg

IWP-2 is an inhibitor of Wntprocessing and secretion with IC50of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.

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Description

IWP-2 is an inhibitor of Wntprocessing and secretion with IC50of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.