IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κBand JNK/AP1signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1)degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.
Price | 1.597,00 RON (preturile sunt fara TVA) |
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Description |
IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κBand JNK/AP1signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1)degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux. |