Limba
Romanian
Romanian
English|
I-138 is an orally active, potent reversible inhibitor of USP1-UAF1with IC50 0f 4.1 nM. I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells.
| Price | 10.848,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
I-138 is an orally active, potent reversible inhibitor of USP1-UAF1with IC50 0f 4.1 nM. I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells. |
