HM43239, 5mg

HM43239, 5mg

HM43239, 1g

HM43239, 1g

HM43239, 100mg

6.475,98 RON
SKU
SKM_S9892_100mg

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s’ of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.

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Description

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s’ of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.