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Romanian
Romanian
English|
Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγand cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptorwith Ki of 397 nM.
| Price | 992,00 RON (preturile sunt fara TVA) |
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| Description |
Harmine (Telepathine), a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value for DYRK2. Harmine also inhibits monoamine oxidases (MAOs), PPARγand cdc-like kinases (CLKs). Harmine inhibits 5-HT2A serotonin receptorwith Ki of 397 nM. |
