Limba
Romanian
Romanian
English|
GSK-J1 is a highly potent inhibitor of H3K27 histone demethylaseJMJD3 (KDM6B) and UTX (KDM6A) with IC50of 60 nM in cell-free assays for JMJD3 (KDM6B) , respectively, >10-fold selectivity over other tested demethylases, with IC50of 0.95μM and 1.76μM towards JARID1B/C.
| Price | 2.076,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
GSK-J1 is a highly potent inhibitor of H3K27 histone demethylaseJMJD3 (KDM6B) and UTX (KDM6A) with IC50of 60 nM in cell-free assays for JMJD3 (KDM6B) , respectively, >10-fold selectivity over other tested demethylases, with IC50of 0.95μM and 1.76μM towards JARID1B/C. |
