Limba
Romanian
Romanian
English|
Gossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5α-reductase 1and 3α-hydroxysteroid dehydrogenasewith IC50 of 3.33 μM and 0.52 μM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 μM and 10 μM for Bcl-XLand Bcl-2, respectively. Gossypol induces apoptosisand cell growth inhibition in various cancer cells.
| Price | 2.197,00 RON (preturile sunt fara TVA) |
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| Description |
Gossypol (BL 193) is an orally-active polyphenol isolated from cotton seeds and roots. Gossypol is a potent inhibitor of 5α-reductase 1and 3α-hydroxysteroid dehydrogenasewith IC50 of 3.33 μM and 0.52 μM in cell-free assay, respectively. Gossypol also inhibits the binding of BH3 peptide to Bcl protein with IC50 of 0.4 μM and 10 μM for Bcl-XLand Bcl-2, respectively. Gossypol induces apoptosisand cell growth inhibition in various cancer cells. |
