GMB-475, 25mg

GMB-475, 25mg

MZ-1, 2mg

MZ-1, 2mg

GMB-475, 10mM/1mL

2.470,44 RON
SKU
SKM_S8888_10mM/1mL

GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1protein and recruit the E3 ligaseVon Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.

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Description

GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1protein and recruit the E3 ligaseVon Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.