H3B-6527, 10mM/1mL

H3B-6527, 10mM/1mL

Glumetinib, 25mg

Glumetinib, 25mg

Glumetinib, 5mg

1.331,61 RON
SKU
SKM_S8676_5mg

Glumetinib is a potent and highly selective c-Metinhibitor with an IC50 of 0.42 ± 0.02 nmol/L. Glumetinib has greater than 2,400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, and TyrO3.

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Description

Glumetinib is a potent and highly selective c-Metinhibitor with an IC50 of 0.42 ± 0.02 nmol/L. Glumetinib has greater than 2,400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, and TyrO3.