Gefitinib-based PROTAC 3  , 100mg

Gefitinib-based PROTAC 3 , 100mg

RU-301, 5mg

RU-301, 5mg

Gefitinib-based PROTAC 3 , 10mM/1mL

3.255,84 RON
SKU
SKM_S0070_10mM/1mL

Gefitinib-based PROTAC 3 which conjugates an EGFR binding element to a VHL ligand via a linker induces degradation of EGFRand mutants with DC50 of 11.7 nM and 22.3 nM in HCC827(Exon 19 del) and H3255 (L858R) cells, respectively.

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Description

Gefitinib-based PROTAC 3 which conjugates an EGFR binding element to a VHL ligand via a linker induces degradation of EGFRand mutants with DC50 of 11.7 nM and 22.3 nM in HCC827(Exon 19 del) and H3255 (L858R) cells, respectively.