Limba
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Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptorwith IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimersand hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough.
Price | 2.125,00 RON (preturile sunt fara TVA) |
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Description |
Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptorwith IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimersand hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough. |