ASP4132, 25mg

ASP4132, 25mg

G10 (STING agonist-1), 25mg

G10 (STING agonist-1), 25mg

G10 (STING agonist-1), 5mg

1.180,48 RON
SKU
SKM_S8954_5mg

G10 (STING agonist-1) is a novel human-specific STINGagonist that triggers IFN regulatory factor 3 (IRF3)/ type I interferon (IFN)-associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM.

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Description

G10 (STING agonist-1) is a novel human-specific STINGagonist that triggers IFN regulatory factor 3 (IRF3)/ type I interferon (IFN)-associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM.