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Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met)and KDRwith IC50of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
| Price | 1.119,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Foretinib is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met (c-Met)and KDRwith IC50of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit (c-Kit), PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2. |
