Fedratinib (TG101348), 1g

Fedratinib (TG101348), 1g

PAC-1, 10mg

PAC-1, 10mg

Fedratinib (TG101348), 10mM/1mL

1.651,72 RON
SKU
SKM_S2736_10mM/1mL

Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2with IC50of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3)and RET (c-RET)with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.

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Price 1.388,00 RON (preturile sunt fara TVA)
Description

Fedratinib (SAR302503, TG101348) is a selective inhibitor of JAK2with IC50of 3 nM in cell-free assays, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Fedratinib also inhibits FMS-like tyrosine kinase 3 (FLT3)and RET (c-RET)with IC50 of 15 nM and 48 nM, respectively. Fedratinib has potential antineoplastic activity. Fedratinib inhibits proliferation and induces apoptosis. Phase 2.