Limba
Romanian
Romanian
English|
Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase)with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosistranscriptional program in acute myeloid leukemia (AML) cells via activation of AP-1transcription factors.
| Price | 1.801,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Farudodstat(LAS 186323,ASLAN003) is a potent and orally active inhibitor of DHODH (Dihydroorotate dehydrogenase)with IC50 of 35 nM for human DHODH enzyme activity. ASLAN003 impairs protein synthesis and induces the differentiation and apoptosistranscriptional program in acute myeloid leukemia (AML) cells via activation of AP-1transcription factors. |
