Limba
Romanian
Romanian
English|
ENMD-2076 has selective activity against Aurora Aand Flt3with IC50of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFRα. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 μM, which induces apoptosisand G2/M phase arrest. Phase 2.
| Price | 1.603,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
ENMD-2076 has selective activity against Aurora Aand Flt3with IC50of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFRα. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 μM, which induces apoptosisand G2/M phase arrest. Phase 2. |
