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Doramapimod (BIRB 796), 200mg
9.688,98 RON
SKU
SKM_S1574_200mg
Doramapimod (BIRB 796) is a pan-p38 MAPKinhibitor with IC50of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38αwith Kdof 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.
| Price | 8.142,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Doramapimod (BIRB 796) is a pan-p38 MAPKinhibitor with IC50of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38αwith Kdof 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2. |
