Limba
Romanian
Romanian
English|
Doramapimod (BIRB 796), 10mM/1mL
2.122,96 RON
SKU
SKM_S1574_10mM/1mL
Doramapimod (BIRB 796) is a pan-p38 MAPKinhibitor with IC50of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38αwith Kdof 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2.
| Price | 1.784,00 RON (preturile sunt fara TVA) |
|---|---|
| Description |
Doramapimod (BIRB 796) is a pan-p38 MAPKinhibitor with IC50of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ in cell-free assays, and binds p38αwith Kdof 0.1 nM in THP-1 cells, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2. |
