Dinaciclib, 5mg

Dinaciclib, 5mg

Dinaciclib, 1g

Dinaciclib, 1g

Dinaciclib, 200mg

10.978,94 RON
SKU
SKM_S2768_200mg

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1and CDK9with IC50of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.

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Description

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1and CDK9with IC50of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.