Dinaciclib, 1g

Dinaciclib, 1g

MK-5108, 5mg

MK-5108, 5mg

Dinaciclib, 10mM/1mL

1.986,11 RON
SKU
SKM_S2768_10mM/1mL

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1and CDK9with IC50of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.

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Description

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1and CDK9with IC50of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.