Demethyleneberberine, 1mg

Demethyleneberberine (DMB), a component of Cortex Phellodendri Chinensis (CPC), significantly alleviates the weight loss and diminishes myeloperoxidase (MPO)activity, while significantly reduces the production of pro-inflammatory cytokines, such as interleukin (IL)-6and tumor necrosis factor-α (TNF-α), and inhibits the activation of NF-κBsignaling pathway. Demethyleneberberine (DMB) potentially ameliorates NAFLD (Non-alcoholic fatty liver disease) by activating AMPKpathways.